FOXA1 anticorps (AA 7-103)
Aperçu rapide pour FOXA1 anticorps (AA 7-103) (ABIN6972166)
Antigène
Voir toutes FOXA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 7-103
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Attributs du produit
- HNF-3a (Hepatocyte nuclear factor 3 alpha, forkhead box A1, FoxA1) is a homeodomain containing transcription factor and is a member of the Hepatocyte Nuclear Factor family (HNF-1a, HNF-1b, HNF-3a, HNF-3b, HNF-3g, HNF-4a, HNF-4g, HNF-6a and HNF-6b), whose members regulate the transcription of numerous hepatocyte genes in adult liver. HNF-3 members bind to DNA as monomers using a winged helix DNA-binding domain. HNF-3a and HNF-3g have also been shown to be involved in gastrulation events such as body axis formation. HNF-3a / FOXA1 antibody (mAb) (Clone 2F83) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Immunohistochemistry and Western blot, it has been shown to react with Human and Mouse samples.
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Purification
- Protein G Chromatography
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Immunogène
- This HNF-3α / FOXA1 antibody was raised against a recombinant protein corresponding to amino acids 7-103 of rat HNF-3α /FOXA1.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- FOXA1 (Forkhead Box A1 (FOXA1))
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Autre désignation
- HNF-3α / FOXA1
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Poids moléculaire
- 50 kDa
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NCBI Accession
- NP_036874
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis
Antigène
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