IRF2 anticorps (C-Term)
Aperçu rapide pour IRF2 anticorps (C-Term) (ABIN6972209)
Antigène
Voir toutes IRF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Attributs du produit
- IRF-2 (interferon regulatory factor 2) specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. IRF-2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
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Purification
- Affinity Purified
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Immunogène
- This IRF-2 antibody was raised against a peptide within the C-terminal region of human IRF-2.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- IRF2 (Interferon Regulatory Factor 2 (IRF2))
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Autre désignation
- IRF-2
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Poids moléculaire
- 39 kDa
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NCBI Accession
- NP_002190
Antigène
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