MED1 anticorps (C-Term)

N° du produit ABIN6972331

Détail du produit anti-MED1 anticorps

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: MED1 (Mediator complex subunit 1, TRIP2, Thyroid receptor-interacting protein 2) is a component of the Mediator complex, a coactivator involved in the regulated transcription of most genes transcribed by RNA polymerase II. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. MED1 is involved in supporting hematopoietic stem and/or progenitor cell function. MED1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This MED1 antibody was raised against a peptide within the C-terminal region of human MED1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur MED1

Antigène: MED1 (Mediator Complex Subunit 1 (MED1))

Autre désignation: MED1 (MED1 Produits)

Synonymes: anticorps CRSP1, anticorps CRSP200, anticorps DRIP205, anticorps DRIP230, anticorps PBP, anticorps PPARBP, anticorps PPARGBP, anticorps RB18A, anticorps TRAP220, anticorps TRIP2, anticorps CRSP-1, anticorps MED1, anticorps pbp, anticorps nbr1, anticorps crsp1, anticorps rb18a, anticorps trip2, anticorps pparbp, anticorps crsp200, anticorps drip205, anticorps drip230, anticorps ppargbp, anticorps trap220, anticorps CG7162, anticorps Dmel\\CG7162, anticorps Med1, anticorps Med1/SOP3/TRAP220, anticorps Trap220, anticorps dTRAP220, anticorps AI480703, anticorps CRSP210, anticorps Pparbp, anticorps l11Jus15, anticorps RGD1559552, anticorps mediator complex subunit 1, anticorps calcitonin-related polypeptide beta, anticorps Mediator complex subunit 1, anticorps mediator of RNA polymerase II transcription subunit 1, anticorps MED1, anticorps CALCB, anticorps med1, anticorps Med1

Poids moléculaire: 210 kDa

NCBI Accession: NP_004765

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha