MED15 anticorps (C-Term)
Aperçu rapide pour MED15 anticorps (C-Term) (ABIN6972333)
Antigène
Voir toutes MED15 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Attributs du produit
- MED15 (mediator of RNA polymerase II transcription subunit 15) is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway. MED15 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.
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Purification
- Affinity Purified
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Immunogène
- This antibody was raised against a peptide within the C-terminal region of human MED15.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- MED15 (Mediator Complex Subunit 15 (MED15))
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Autre désignation
- MED15
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Poids moléculaire
- 100 kDa
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NCBI Accession
- NP_001003891
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Pathways
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Antigène
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