PRMT6 anticorps (N-Term)

N° du produit ABIN6972556

Cet anticorps anti-PRMT6 Polyclonal Lapin (ABIN6972556) détecte spécifiquement PRMT6 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PRMT6 anticorps (N-Term) (ABIN6972556)

Antigène: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRMT6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PRMT6 anticorps

Épitope: N-Term

Attributs du produit: PRMT6 (Protein Arginine Methyltransferase 6, HRMT1L6, ANM6) is a type I arginine methyltransferase. Arginine methylation is a common post-translational modification of histones and other cellular proteins. PRMT6 preferentially methylates arginine residues present in GAR (glycine and arginine-rich) domains. PRMT6 asymmetrically dimethylates histone H3 at Arg2, which is mutually exclusive to methylation at lysine 4 (associated with transcriptional activation), and thus PRMT6 serves as a transcriptional repressor in this context. It can also symmetrically dimethylate H2A and H4 at Arg3 and serves as a coactivator of transcription in concert with nuclear receptors. PRMT6 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunohistochemistry and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This PRMT6 antibody was raised against a peptide corresponding to amino acids within the N-terminal region of PRMT6.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur PRMT6

Antigène: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Autre désignation: PRMT6

Poids moléculaire: 42 kDa

NCBI Accession: NP_060607