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Recombinant SARS-CoV-2 Spike IgG/IgM anticorps

Reactivité: SARS Coronavirus-2 (SARS-CoV-2) ELISA Hôte: Human Monoclonal AM043105 (105-43) unconjugated Recombinant Antibody
N° du produit ABIN6972694
  • Antigène
    SARS-CoV-2 Spike IgG/IgM
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    SARS Coronavirus-2 (SARS-CoV-2)
    Hôte
    Human
    Clonalité
    Monoclonal
    Application
    ELISA
    Attributs du produit
    COVID-19, which is short for coronavirus disease 2019, is the official name of the respiratory disease caused by infection with the novel coronavirus SARS-CoV-2. The virus that causes COVID-19 was named SARS-CoV-2 because it is a coronavirus genetically similar to, yet distinct from, the virus that caused the severe acute respiratory syndrome (SARS) outbreak in 2003. Studying the details of how this virus replicates and causes the disease will allow scientists and physicians to more rapidly develop fast and accurate methods of detection as well as to deploy therapeutic and vaccine strategies. This antibody was derived from COVID-19 patients who have cleared the virus. Patient serum IgG was sequenced and expressed as a chimeric full-length human immunoglobulin in mammalian 293 cells. This chimeric antibody contains a heavy chain CH1 that is IgG1 isotype, whereas its CH2/CH3/CH4 regions are IgM isotype. The antibody contains a Flag Tag and an 8X His Tag at the C-terminus. SARS-CoV-2 Spike IgG/IgM Antibody (AM5) (Clone AM5 (105-43)) was raised in a Human host. It has been validated for use in ELISA, it has been shown to react with Virus samples.
    Purification
    Ni-NTA
    Immunogène
    Derived from COVID-19 patients who have cleared the virus. Their antibodies were screened for reactivity to SARS-CoV-2 and then sequenced and expressed as recombinant antibodies.
    Clone
    AM043105 (105-43)
    Isotype
    IgG, IgM
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS, 30 % glycerol, 0.035 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Antigène
    SARS-CoV-2 Spike IgG/IgM
    Classe de substances
    Antibody
    Poids moléculaire
    141 kDa (full length S1 protein)
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