MREG anticorps (AA 101-200) (AbBy Fluor® 350)

N° du produit ABIN6976543

Cet anticorps Lapin Polyclonal détecte spécifiquement MREG dans WB, IF (p) et IF (cc). Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour MREG anticorps (AA 101-200) (AbBy Fluor® 350) (ABIN6976543)

Antigène: MREG (Melanoregulin (MREG))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MREG est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-MREG anticorps (AbBy Fluor® 350)

Épitope: AA 101-200

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DSU

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MREG

Antigène: MREG (Melanoregulin (MREG))

Autre désignation: DSU

Sujet:

Synonyms: Dilute suppressor, Dilute suppressor protein homolog, DSU, FLJ10116, MREG_HUMAN, Melanoregulin, MGC90296, MREG, OTTHUMP00000206794, OTTHUMP00000206795, OTTHUMP00000206796, WDT 2, WDT2, Whn dependent transcript 2.

Background: The photoreceptor rod cell that is responsible for vision under conditions of low light consists of stacked arrays of disk membranes that make up its outer segment portion. Regulated by complex biochemical mechanisms, the rod outer segment is under constant renewal as new disks form at the base. MREG (melanoregulin), also known as DSU (dilute suppressor protein homolog) or WDT2, is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG interacts with RDS (also known as Peripherin-2), a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. MREG is 214 amino acids in length, is expressed in photoreceptor cells and and is expressed as two isoforms due to alternative splicing.

ID gène: 55686

UniProt: Q8N565