IMPACT anticorps (AA 21-120) (AbBy Fluor® 555)

N° du produit ABIN6978336

Cet anticorps anti-IMPACT est un anticorps Lapin Polyclonal détectant IMPACT dans WB, IF (cc) et IF (p). Adapté pour Souris et Rat.

Aperçu rapide pour IMPACT anticorps (AA 21-120) (AbBy Fluor® 555) (ABIN6978336)

Antigène: IMPACT (Impact Homolog (IMPACT))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IMPACT est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-IMPACT anticorps (AbBy Fluor® 555)

Épitope: AA 21-120

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IMPACT

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur IMPACT

Antigène: IMPACT (Impact Homolog (IMPACT))

Autre désignation: IMPACT

Sujet:

Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog

Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).

ID gène: 55364

UniProt: Q9P2X3