Calsequestrin anticorps (AA 1-100) (AbBy Fluor® 594)

N° du produit ABIN6979427

L’anticorps Lapin Polyclonal anti-Calsequestrin a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter Calsequestrin dans des échantillons de Humain.

Aperçu rapide pour Calsequestrin anticorps (AA 1-100) (AbBy Fluor® 594) (ABIN6979427)

Antigène: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calsequestrin est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Calsequestrin anticorps (AbBy Fluor® 594)

Épitope: AA 1-100

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Calsequestrin

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Calsequestrin

Antigène: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Autre désignation: Calsequestrin-1

Sujet:

Synonyms: CASQ, Calsequestrin 1, Calsequestrin 1 fast twitch skeletal muscle, Calsequestrin skeletal muscle isoform, CASQ 1, CASQ1, PDIB1, Skeletal muscle calsequestrin 1, Calmitine.

Background: The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.

ID gène: 844

UniProt: P31415