Importin 8 anticorps (AA 1-100) (AbBy Fluor® 680)

N° du produit ABIN6981177

Cet anticorps anti-Importin 8 est un anticorps Lapin Polyclonal détectant Importin 8 dans IF (cc) et IF (p). Adapté pour Rat.

Aperçu rapide pour Importin 8 anticorps (AA 1-100) (AbBy Fluor® 680) (ABIN6981177)

Antigène: Importin 8 (IPO8)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Importin 8 est conjugé à/à la AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Importin 8 anticorps (AbBy Fluor® 680)

Épitope: AA 1-100

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Importin 8

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Importin 8

Antigène: Importin 8 (IPO8)

Autre désignation: Importin 8

Sujet:

Synonyms: FLJ26580, Imp 8, Imp8, Importin-8, Importin8, IPO 8, IPO8, IPO8_HUMAN, Ran binding protein 8, RAN BP8, Ran-binding protein 8, RANBP 8, RANBP8.

Background: Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.

ID gène: 10526

UniProt: O15397