FERMT1 anticorps (AA 601-677) (AbBy Fluor® 750)

N° du produit ABIN6981898

Cet anticorps Lapin Polyclonal détecte spécifiquement FERMT1 dans IF (cc) et IF (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour FERMT1 anticorps (AA 601-677) (AbBy Fluor® 750) (ABIN6981898)

Antigène: FERMT1 (Fermitin Family Member 1 (FERMT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FERMT1 est conjugé à/à la AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-FERMT1 anticorps (AbBy Fluor® 750)

Épitope: AA 601-677

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Kindlin

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FERMT1

Antigène: FERMT1 (Fermitin Family Member 1 (FERMT1))

Autre désignation: Kindlin

Sujet:

Synonyms: C20orf42, Chromosome 20 open reading frame 42, DTGCU 2, DTGCU2, FERM1_HUMAN, Fermitin family homolog 1, Fermt1, FLJ20116, FLJ23423, KIND 1, KIND1, Kinderlin, Kindlerin, Kindlin 1, Kindlin syndrome protein, Kindlin-1, Kindlin1, Unc 112 related protein 1, Unc-112-related protein 1, Unc112 related protein, UNC112A, URP 1, URP1.

Background: Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

ID gène: 55612

UniProt: Q9BQL6