MAP2 anticorps (pThr1613, pThr1619) (Biotin)

N° du produit ABIN6982618

Détail du produit anti-MAP2 anticorps (Biotin)

Antigène: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Épitope: pThr1613, pThr1619

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthesised phosphopeptide derived from human MAP2 around the phosphorylation site of Thr1613 and Thr1619

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MAP2

Antigène: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Autre désignation: MAP2 (MAP2 Produits)

Synonymes: anticorps MAP2A, anticorps MAP2B, anticorps MAP2C, anticorps MAP2R, anticorps Mtap2, anticorps MAP-2, anticorps Mtap-2, anticorps xmap2, anticorps MGC53131, anticorps a730034c02, anticorps zgc:103474, anticorps zgc:113974, anticorps microtubule associated protein 2, anticorps microtubule-associated protein 2, anticorps microtubule associated protein 2 S homeolog, anticorps MAP2, anticorps Map2, anticorps map2.S, anticorps map2

Sujet:

Synonyms: MAP2(Phospho Thr1613/1619), MAP2 (phospho Thr1613/1619), p-MAP2 (phospho Thr1613/1619), MAP2(Phospho Thr1613/1619), MAP2(Phospho-Thr1613/1619), p-MAP2(Phospho-Thr1613/1619), DKFZp686I2148, Dendrite specific MAP, DKFZp686I2148, MAP 2, MAP-2, MAP2, MAP2_HUMAN, MAP2A, MAP2B, MAP2C, Microtubule associated protein 2, Microtubule-associated protein 2, Mtap 2.

Background: MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2, two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.

ID gène: 4133

UniProt: P11137