Latrophilin 1 anticorps (AA 201-300) (Biotin)

N° du produit ABIN6982672

Cet anticorps Lapin Polyclonal détecte spécifiquement Latrophilin 1 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour Latrophilin 1 anticorps (AA 201-300) (Biotin) (ABIN6982672)

Antigène: Latrophilin 1 (LPHN1)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Latrophilin 1 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Latrophilin 1 anticorps (Biotin)

Épitope: AA 201-300

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LPHN1

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Latrophilin 1

Antigène: Latrophilin 1 (LPHN1)

Autre désignation: LPHN1

Sujet:

Synonyms: Calcium independent alpha latrotoxin receptor 1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, CIRL1, CL1, CLIBA, G protein-coupled receptor for alpha-Latrotoxin, KIAA0821, Latrophilin 1, Latrophilin-1, Latrophilin1, LEC2, Lectomedin 2, Lectomedin-2, LPHN 1, LPHN1, LPHN1_HUMAN.

Background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

ID gène: 22859

UniProt: O94910

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis