Recombinant kappa Light Chain anticorps (AA 1-107) (Biotin)

N° du produit ABIN6983160

Cet anticorps anti-kappa Light Chain Monoclonal Lapin conjugué à Biotin (ABIN6983160) détecte spécifiquement kappa Light Chain dans WB, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant kappa Light Chain anticorps (AA 1-107) (Biotin) (ABIN6983160)

Antigène: kappa Light Chain

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp kappa Light Chain est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-kappa Light Chain anticorps (Biotin)

Épitope: AA 1-107

Fonction: Human Ig Kappa light chain Recombinant Antibody, Biotin Conjugated

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Full length native human IgG.

Isotype: IgG

Information d'application

Indications d'application: WB(WB(1:500-2000)), IHC-P(IHC-P(1:100-500)), IHC-F(IHC-F(1:100-500))

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur kappa Light Chain

Antigène: kappa Light Chain

Sujet:

Synonyms: Kappa Light Chain, IGKC, HCAK 1, HCAK1, Ig kappa chain C region, IGKC, Immunoglobulin kappa constant, Immunoglobulin kappa constant region, Immunoglobulin kappa light chain, Kappa 1 immunoglobulin light chain, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809, Human Ig/L-Chain Kappa, IGKC_HUMAN.

Background: Immunoglobulins belong to a group of related glyco proteins which make up 20 % of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit, while, IgM is a pen tamer. IgA may also form polymers.
Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.

ID gène: 3514

UniProt: P01834