NCR1 anticorps (AA 1-100) (FITC)

N° du produit ABIN6987340

Cet anticorps Lapin Polyclonal détecte spécifiquement NCR1 dans IF (p) et IF (cc). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour NCR1 anticorps (AA 1-100) (FITC) (ABIN6987340)

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCR1 est conjugé à/à la FITC

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-NCR1 anticorps (FITC)

Épitope: AA 1-100

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NCR1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur NCR1

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: NCR1

Sujet:

Synonyms: Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1, NK-p46, NKp46, NK cell-activating receptor, Lymphocyte antigen 94 homolog, CD335, CD 335, LY94, NCTR1_HUMAN.

Background: The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

ID gène: 9437

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity