PLA2G6 anticorps (AA 331-430)

N° du produit ABIN6989060

L’anticorps anti-PLA2G6 Polyclonal Lapin est utilisé pour la détection de PLA2G6 dans des échantillons de Humain. Il a été validé pour ICC, IF, IHC (p) et IHC (fro).

Aperçu rapide pour PLA2G6 anticorps (AA 331-430) (ABIN6989060)

Antigène: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLA2G6 est non-conjugé

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PLA2G6 anticorps

Épitope: AA 331-430

Fonction: CaIPLA2 Polyclonal Antibody

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CaIPLA2

Isotype: IgG

Information d'application

Indications d'application: IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500), ICC/IF(1:100-500)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PLA2G6

Antigène: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Autre désignation: CaIPLA2

Sujet:

Synonyms: 85 kDa calcium independent phospholipase A2, 85 kDa calcium-independent phospholipase A2, CaI PLA2, CaI-PLA2, CaIPLA2, Calcium independent phospholipase A2, Cytosolic calcium independent phospholipase A2, Group VI phospholipase A2, GVI, GVI PLA2, INAD1, iPLA(2)beta, iPLA2, IPLA2 VIA, iPLA2beta, NBIA2A, NBIA2B, PA2G6_HUMAN, PARK14, Patatin like phospholipase domain containing 9, Patatin like phospholipase domain containing protein 9, Phospholipase A2 calcium independent, Phospholipase A2 calcium independent group VI A, Phospholipase A2 group VI, Phospholipase A2 group VI cytosolic calcium independent, PLA2, PLA2G6, PNPLA9, PLPL9_HUMAN

Background: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.
Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.

ID gène: 8398

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion