ALOX15 anticorps (AA 600-650)

N° du produit ABIN6989093

L’anticorps Lapin Polyclonal anti-ALOX15 a été validé pour WB, IF, IHC (p) et IHC (fro). Il convient pour détecter ALOX15 dans des échantillons de Humain.

Aperçu rapide pour ALOX15 anticorps (AA 600-650) (ABIN6989093)

Antigène: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX15 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ALOX15 anticorps

Épitope: AA 600-650

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ALOX15

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IF()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ALOX15

Antigène: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Autre désignation: ALOX15

Sujet:

Synonyms: 15 lipoxygenase 1, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 LOX, 15 LOX 1, 15-LOX, 15LOX 1, ALOX15, Arachidonate 15 lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate omega 6 lipoxygenase, Arachidonate omega-6 lipoxygenase, LOG15, LOX15_HUMAN.

Background: Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes and synthesis of signaling molecules, as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals include 12-LO and 15-LO, which are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase (15-LO) acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation, and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation.

ID gène: 246

UniProt: P16050

Pathways: Regulation of Actin Filament Polymerization