SMAD9 anticorps (AA 351-450)
Aperçu rapide pour SMAD9 anticorps (AA 351-450) (ABIN6989418)
Antigène
Voir toutes SMAD9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 351-450
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Réactivité croisée
- Humain, Souris, Rat, Poisson zèbre (Danio rerio)
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human SMAD8
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Isotype
- IgG
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Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- SMAD9 (SMAD Family Member 9 (SMAD9))
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Autre désignation
- SMAD8
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Sujet
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Synonyms: AI528653 , BSP 1 , BSP1 , DKFZp781C1895 , DKFZp781O1323 , Dwarfin A , Dwf A , DwfA , Dwfc , hSMAD1 , hSmad5 , JV 41 , JV4 1 , JV41 , JV5 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 9 , MAD homolog 1 , MAD homolog 9 , MAD homolog1 (mothers against decapentaplegic, Drosophila) ,
Background: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway
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ID gène
- 142891
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UniProt
- Q96LT4
Antigène
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