Estrogen Receptor alpha anticorps (pSer106)

N° du produit ABIN6989480

L’anticorps Lapin Polyclonal anti-Estrogen Receptor alpha a été validé pour ELISA, FACS, IHC (p), IF (cc), IF (p), ICC et IHC (fro). Il convient pour détecter Estrogen Receptor alpha dans des échantillons de Humain et Rat.

Aperçu rapide pour Estrogen Receptor alpha anticorps (pSer106) (ABIN6989480)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Estrogen Receptor alpha anticorps

Épitope: pSer106

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated Synthesised phosphopeptide derived from human ER alpha around the phosphorylation site of Ser106

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: Estrogen Receptor alpha

Sujet:

Synonyms: Estrogen Receptor alpha (phospho S106), p-Estrogen Receptor alpha (phospho S106), DKFZp686N23123, ER alpha, ER, ER-alpha, Era, ESR, ESR1, ESR1_HUMAN, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Estrogen receptor 1, Estrogen receptor alpha 3*,4,5,6,7*/822 isoform, Estrogen receptor alpha delta 3*,4,5,6,7*,8*/941 isoform, Estrogen receptor alpha delta 3*,4,5,6,7*/819 2 isoform, Estrogen receptor alpha delta 4 +49 isoform, Estrogen receptor alpha delta 4*,5,6,7*/654 isoform, Estrogen receptor alpha delta 4*,5,6,7,8*/901 isoform, Estrogen receptor, NR3A1, Nuclear receptor subfamily 3 group A member 1.

Background: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]

ID gène: 2099

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly