Recombinant CHMP2B anticorps

N° du produit ABIN6989680

Cet anticorps Lapin Monoclonal détecte spécifiquement CHMP2B dans WB, IF, ICC, FACS et IP. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant CHMP2B anticorps (ABIN6989680)

Antigène: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CHMP2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Détail du produit anti-CHMP2B anticorps

Fonction: CHMP2B Recombinant Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Synthetic Peptide within Human CHMP2B.

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IP(1:20-100), Flow-Cyt(1:200-400), ICC/IF(1:50-100)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CHMP2B

Antigène: CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

Autre désignation: CHMP2B

Sujet:

Synonyms: ALS17 antibody, Charged multivesicular body protein 2b antibody, CHM2B_HUMAN antibody, CHMP family, member 2B antibody, CHMP2.5 antibody, CHMP2b antibody, Chromatin modifying protein 2b antibody, Chromatin-modifying protein 2b antibody, DMT1 antibody, hVps2-2 antibody, Vacuolar protein sorting 2, yeast, homolog of, B antibody, Vacuolar protein sorting 2-2 antibody, Vacuolar protein sorting-associated protein 2-2 antibody, VPS2 homolog B antibody, Vps2-2 antibody, VPS2B antibody

Background: The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).

ID gène: 25978

UniProt: Q9UQN3