SAV1 anticorps

N° du produit ABIN6989879

L’anticorps Lapin Polyclonal anti-SAV1 a été validé pour WB et IHC. Il convient pour détecter SAV1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SAV1 anticorps (ABIN6989879)

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAV1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SAV1 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein of human SAV1.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SAV1

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Autre désignation: SAV1

Sujet: Optional[synonyms]: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]

ID gène: 60485

UniProt: Q9H4B6

Pathways: Stem Cell Maintenance