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SARS-CoV-2 Membrane Protein anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-SARS-CoV-2 Membrane Protein a été validé pour ELISA et WB. Il convient pour détecter SARS-CoV-2 Membrane Protein dans des échantillons de SARS Coronavirus-2 (SARS-CoV-2) et SARS Coronavirus (SARS-CoV).
N° du produit ABIN6990122

Aperçu rapide pour SARS-CoV-2 Membrane Protein anticorps (C-Term) (ABIN6990122)

Antigène

SARS-CoV-2 Membrane Protein (SARS-CoV-2 M)

Reactivité

SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)

Hôte

  • 3
  • 2
Lapin

Clonalité

  • 5
Polyclonal

Conjugué

  • 5
Cet anticorp SARS-CoV-2 Membrane Protein est non-conjugé

Application

  • 5
  • 3
  • 3
ELISA, Western Blotting (WB)
  • Épitope

    • 2
    • 1
    • 1
    • 1
    C-Term

    Purification

    SARS-CoV-2/SARS-CoV Matrix Antibody is affinity chromatography purified via peptide column.

    Immunogène

    Anti-SARS-CoV-2/SARS-CoV Matrix antibody was raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of SARS-CoV Matrix protein. The immunogen is located within the last 50 amino acids of SARS-CoV Matrix.

    Isotype

    IgG
  • Indications d'application

    WB: 1 μ,g/mL.

    Antibody validated: SARS-CoV-2/SARS-CoV Matrix antibody can be used for the detection of SARS-CoV-2/SARS-CoV Matrix protein in ELISA. It will detect 5 ng of free peptide at 1 μ,g/mL.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    SARS-CoV-2/SARS-CoV Matrix Antibody is supplied in PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,4 °C

    Stockage commentaire

    SARS-CoV-2/SARS-CoV Matrix antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène

    SARS-CoV-2 Membrane Protein (SARS-CoV-2 M)

    Autre désignation

    SARS-CoV-2 Membrane Protein

    Classe de substances

    Viral Protein

    Sujet

    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019-20 coronavirus outbreak (1). SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10 (2).The membrane (M) protein or matrix protein is the most abundant structural protein and defines the shape of the viral envelope (3). It is an integral membrane protein involved in the budding of the viral particles and interacts with S (Spike) protein. It involves in organization of the nucleoprotein inside, which includes many copies of the N (nucleocapsid) protein bound to the genomic RNA. The M protein holds dominant cellular immunogenicity and has been determined as a protective antigen in humoral responses, which suggests it would serve as a potential target in vaccine design (4).

    ID gène

    43740571
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