SARS-CoV-2 NSP5 (3CL-Pro) anticorps (N-Term)
Aperçu rapide pour SARS-CoV-2 NSP5 (3CL-Pro) anticorps (N-Term) (ABIN6990134)
Antigène
Voir toutes SARS-CoV-2 NSP5 (3CL-Pro) (3CL-PRO, M-Pro) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Purification
- SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) Antibody is affinity chromatography purified via peptide column.
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Immunogène
- Anti-SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of SARS-CoV-2 (COVID-19) 3CL-Pro (NSP5) protein. The immunogen is located within the first 50 amino acids of the SARS-CoV-2 (COVID-19) 3CL-Pro (NSP5) protein.
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Isotype
- IgG
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Indications d'application
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IHC: 0.5 μ,g/mL, WB: 0.5 μ,g/mL
Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 NSP5 recombinant protein by ELISA and WB. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) antibody can be stored at 4 ° C for three months and -20 ° C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SARS-CoV-2 NSP5 (3CL-Pro) (3CL-PRO, M-Pro) (SARS-CoV-2 3C-Like Proteinase (NSP5) (3CL-PRO, M-Pro))
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Autre désignation
- SARS-CoV-2 3CL-PRO
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Classe de substances
- Viral Protein
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Sujet
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. 3C- like proteinase (NSP5) cleaves the C-terminus of replicase polyprotein at 11 sites (3,4,5). It recognizes substrates containing the core sequence [ILMVF]-Q-|-[SGACN]. It also able to bind an ADP-ribose-1''-phosphate (ADRP) (5).
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ID gène
- 43740578
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NCBI Accession
- YP_009742612
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UniProt
- P0DTC1
Antigène
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