SARS-CoV-2 NSP14 anticorps (AA 120-170)

N° du produit ABIN6990150

Cet anticorps anti-SARS-CoV-2 NSP14 est un anticorps Lapin Polyclonal détectant SARS-CoV-2 NSP14 dans ELISA et IHC. Adapté pour SARS Coronavirus-2 (SARS-CoV-2).

Aperçu rapide pour SARS-CoV-2 NSP14 anticorps (AA 120-170) (ABIN6990150)

Antigène: SARS-CoV-2 NSP14 (ExoN) (SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14) (ExoN))

Reactivité: SARS Coronavirus-2 (SARS-CoV-2)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SARS-CoV-2 NSP14 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-SARS-CoV-2 NSP14 anticorps

Épitope: AA 120-170

Purification: SARS-CoV-2 (COVID-19) NSP14 (ExoN) Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody was raised against a peptide corresponding to 14 amino acids near the center of SARS-CoV-2 (COVID-19) NSP14 (ExoN) protein. The immunogen is located between 120-170 amino acids of SARS-CoV-2 (COVID-19) NSP14 (ExoN).

Isotype: IgG

Information d'application

Indications d'application: IHC: 0.5 μ,g/mL .

Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. All other applications and species not yet tested

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) NSP14 (ExoN) Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SARS-CoV-2 NSP14

Antigène: SARS-CoV-2 NSP14 (ExoN) (SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14) (ExoN))

Autre désignation: SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14)

Classe de substances: Viral Protein

Sujet: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP14 (ExoN) is an enzyme possessing two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity (3,4,5). It acts as a proofreading exoribonuclease for RNA replication, thereby lowering The sensitivity of the virus to RNA mutagens(6,7,8).

ID gène: 43740578

NCBI Accession: YP_009725309

UniProt: P0DTC1