DC-SIGN/CD209 anticorps

N° du produit ABIN6990166

Cet anticorps Souris Monoclonal détecte spécifiquement DC-SIGN/CD209 dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour DC-SIGN/CD209 anticorps (ABIN6990166)

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DC-SIGN/CD209 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5D7

Détail du produit anti-DC-SIGN/CD209 anticorps

Purification: DC-SIGN Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Immunogène: A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN.

Isotype: IgG1

Information d'application

Indications d'application: DC-SIGN antibody can be used for detection of DC-SIGN in Western Blot at 1 - 2 μ,g/mL and in immunohistochemistry at 5 - 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DC-SIGN Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: DC-SIGN monoclonal antibody can be stored at -20°C, stable for one year.

Détails sur DC-SIGN/CD209

Antigène: DC-SIGN/CD209 (CD209) (CD209)

Autre désignation: DC-SIGN

Sujet: DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.

Poids moléculaire: Predicted: 44 kDa

Observed: 47 kDa

ID gène: 30835

UniProt: Q9NNX6