Hemagglutinin anticorps

N° du produit ABIN6990168

Cet anticorps anti-Hemagglutinin est un anticorps Souris Monoclonal détectant Hemagglutinin dans ELISA. Adapté pour Influenza A Virus H5N1.

Aperçu rapide pour Hemagglutinin anticorps (ABIN6990168)

Antigène: Hemagglutinin (HA)

Reactivité: Influenza A Virus H5N1

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hemagglutinin est non-conjugé

Application: ELISA

Clone: 4F1F2

Détail du produit anti-Hemagglutinin anticorps

Purification: Hemagglutinin Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Immunogène: A peptide corresponding to synthetic peptide corresponding to 14 amino acids in the middle of Hemagglutinin.

Isotype: IgG3

Information d'application

Indications d'application: Hemagglutinin antibody can be used for the detection of the Hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μ,g/mL. Other applications are pending.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Hemagglutinin Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Hemagglutinin monoclonal antibody can be stored at -20°C, stable for one year.

Détails sur Hemagglutinin

Antigène: Hemagglutinin (HA)

Autre désignation: Hemagglutinin

Classe de substances: Influenza Protein

Sujet: Hemagglutinin Monoclonal Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.

UniProt: Q692M2