SIRPA anticorps (C-Term)

N° du produit ABIN6990246

Cet anticorps anti-SIRPA est un anticorps Lapin Polyclonal détectant SIRPA dans WB, ELISA et ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SIRPA anticorps (C-Term) (ABIN6990246)

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRPA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-SIRPA anticorps

Épitope: C-Term

Specificité: Recognizes SIRP alpha 1, 2 and 3.

Purification: SIRP alpha Antibody is affinity chromatography purified via peptide column.

Immunogène: SIRP alpha antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human SIRP alpha 1. The immunogen is located within the last 50 amino acids of SIRP alpha.

Isotype: IgG

Information d'application

Indications d'application: SIRP alpha antibody can be used for Western blot at 0.5 - 1 μ,g/mL. 75 - 110 kDa bands should be detected. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIRP alpha Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SIRP alpha antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: SIRP alpha

Sujet: SIRP alpha Antibody: Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPalpha, SHPS-1, MyD-1, BIT and p84. SIRPalpha is a new gene family containing at least fifteen members. SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPalpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.

Poids moléculaire: 75 - 110 kDa

ID gène: 140885

NCBI Accession: NP_542970

UniProt: P78324