Thymic Stromal Lymphopoietin anticorps (C-Term)

N° du produit ABIN6990253

Cet anticorps Lapin Polyclonal détecte spécifiquement Thymic Stromal Lymphopoietin dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Thymic Stromal Lymphopoietin anticorps (C-Term) (ABIN6990253)

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thymic Stromal Lymphopoietin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Thymic Stromal Lymphopoietin anticorps

Épitope: C-Term

Purification: TSLP Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-TSLP antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TSLP. The immunogen is located within the last 50 amino acids of TSLP.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.25 - 2 μ,g/mL, IHC-P: 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TSLP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TSLP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Thymic Stromal Lymphopoietin

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Autre désignation: TSLP

Sujet: TSLP Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. At least two differentially spliced isoforms of TSLP are known to exist.

Poids moléculaire: Predicted: 18 kD

Observed: 26 kD ( Post-modifications: 2 N-linked glycosylations). kDa

ID gène: 85480

NCBI Accession: NP_149024

UniProt: Q969D9