CIDEB anticorps (C-Term)

N° du produit ABIN6990285

Cet anticorps anti-CIDEB est un anticorps Lapin Polyclonal détectant CIDEB dans ELISA et WB. Adapté pour Souris.

Aperçu rapide pour CIDEB anticorps (C-Term) (ABIN6990285)

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEB est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-CIDEB anticorps

Épitope: C-Term

Specificité: It has no cross activity to CIDE-A.

Purification: CIDE-B Antibody is affinity chromatography purified via peptide column.

Immunogène: CIDE-B antibody was raised against a 16 amino acid peptide near the carboxy terminus of murine CIDE-B. The immunogen is located within the last 50 amino acids of CIDE-B.

Isotype: IgG

Information d'application

Indications d'application: CIDE-B antibody can be used for detection of CIDE-B by Western blot 0.5 μ,g/mL. An approximately 25 kDa band can be detected.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CIDE-B Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CIDE-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CIDEB

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Autre désignation: CIDE-B

Sujet: CIDE-B Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.

Poids moléculaire: 25 kDa

ID gène: 12684

UniProt: O70303