HAVCR1 anticorps (AA 230-280)

N° du produit ABIN6990296

L’anticorps anti-HAVCR1 Polyclonal Lapin est utilisé pour la détection de HAVCR1 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour HAVCR1 anticorps (AA 230-280) (ABIN6990296)

Antigène: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAVCR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HAVCR1 anticorps

Épitope: AA 230-280

Purification: TIM-1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-TIM-1 antibody was raised against a peptide corresponding to 16 amino acids near the center terminus of human TIM-1. The immunogen is located within amino acids 230 - 280 of TIM-1.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-8 μ,g/mL

Antibody validated: Western Blot in human samples. All other applications and species not yet tested

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TIM-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TIM-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur HAVCR1

Antigène: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Autre désignation: TIM-1

Classe de substances: Virus

Sujet: TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.

Poids moléculaire: Predicted: 44kD

Observed: 60kD (Post-modification: 4 N-linked glycosylation) kDa

ID gène: 26762

NCBI Accession: NP_036338

UniProt: Q96D42