BAG4 anticorps (N-Term)

N° du produit ABIN6990302

Détail du produit anti-BAG4 anticorps

Antigène: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purification: SODD Antibody is Antibody is DEAE purified.

Immunogène: SODD antibody was raised against a peptide corresponding to amino acids near the amino terminus of human SODD. The immunogen is located within the first 50 amino acids of SODD.

Isotype: IgG

Information d'application

Indications d'application: SODD antibody can be used for detection of SODD by Western blot at 0.5 μ,g/mL. An approximately 60 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SODD Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SODD antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BAG4

Antigène: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Autre désignation: SODD (BAG4 Produits)

Synonymes: anticorps BAG-4, anticorps SODD, anticorps BAG4, anticorps fd20a04, anticorps wu:fd20a04, anticorps si:dkey-220o5.3, anticorps 2410112I15Rik, anticorps ATBAG4, anticorps BCL-2-associated athanogene 4, anticorps BCL2 associated athanogene 4, anticorps BCL2-associated athanogene 4, anticorps BCL-2-associated athanogene 4, anticorps BAG4, anticorps Bag4, anticorps bag4

Sujet: SODD Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

Poids moléculaire: 60 kDa

ID gène: 9530

UniProt: O95429

Pathways: Regulation of Actin Filament Polymerization