STK17A anticorps (N-Term)
Aperçu rapide pour STK17A anticorps (N-Term) (ABIN6990303)
Antigène
Voir toutes STK17A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- No cross responses to DRAK2, DAP or ZIP kinases.
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Purification
- DRAK1 Antibody is affinity chromatography purified via peptide column.
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Immunogène
- DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1. The immunogen is located within the first 50 amino acids of DRAK1.
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Isotype
- IgG
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Indications d'application
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DRAK1 antibody can be used for detection of DRAK1 by Western blot at 1 μ,g/mL. An approximately 50 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- DRAK1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- DRAK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- STK17A (serine/threonine Kinase 17a (STK17A))
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Autre désignation
- DRAK1
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Sujet
- DRAK1 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
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Poids moléculaire
- 50 kDa
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ID gène
- 9263
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UniProt
- Q9UEE5
Antigène
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