ACIN1 anticorps (C-Term)

N° du produit ABIN6990315

Détail du produit anti-ACIN1 anticorps

Antigène: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Épitope: AA 1050-1100, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACIN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purification: Acinus Antibody is affinity chromatography purified via peptide column.

Immunogène: Acinus antibody was raised against a peptide corresponding to amino acids near the C-terminus of the cleaved active peptide p17, which are identical to those of mouse Acinus. The immunogen is located within amino acids 1050 - 1100 of Acinus.

Isotype: IgG

Information d'application

Indications d'application: Acinus antibody can be used for detection of Acinus by Western blot at 1 μ,g/mL. An approximate 220 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Acinus Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Acinus antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ACIN1

Antigène: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Autre désignation: Acinus (ACIN1 Produits)

Synonymes: anticorps acinus, anticorps acinusb, anticorps fi14c05, anticorps wu:fe06a10, anticorps wu:fi14c05, anticorps acinusa, anticorps acinusl, anticorps ik:tdsubc_2g5, anticorps si:zc14a17.12, anticorps wu:fb04g06, anticorps wu:fb40f03, anticorps wu:fb68h03, anticorps wu:fb80f07, anticorps wu:fc12e10, anticorps xx:tdsubc_2g5, anticorps acn, anticorps ACINUS, anticorps ACN, anticorps fSAP152, anticorps 2610036I19Rik, anticorps 2610510L13Rik, anticorps Acinus, anticorps Acn, anticorps C79325, anticorps acinusL, anticorps acinusS, anticorps mKIAA0670, anticorps apoptotic chromatin condensation inducer 1b, anticorps apoptotic chromatin condensation inducer 1a, anticorps apoptotic chromatin condensation inducer 1, anticorps apoptotic chromatin condensation inducer 1 S homeolog, anticorps acin1b, anticorps acin1a, anticorps acin1, anticorps ACIN1, anticorps acin1.S, anticorps Acin1

Sujet: Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.

Poids moléculaire: 220 kDa

ID gène: 22985

UniProt: Q9UKV3