NOL3 anticorps (C-Term)

N° du produit ABIN6990320

Détail du produit anti-NOL3 anticorps

Antigène: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Nop30 Antibody is affinity chromatography purified via peptide column.

Immunogène: Nop30 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Nop30. The immunogen is located within the last 50 amino acids of Nop30.

Isotype: IgG

Information d'application

Indications d'application: Nop30 antibody can be used for detection of Nop30 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 0.5 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Nop30 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Nop30 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NOL3

Antigène: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Autre désignation: Nop30 (NOL3 Produits)

Synonymes: anticorps ARC, anticorps FCM, anticorps MYP, anticorps NOP, anticorps NOP30, anticorps B430311C09Rik, anticorps MYC, anticorps Nop30, anticorps Arc, anticorps nucleolar protein 3, anticorps nucleolar protein 3 (apoptosis repressor with CARD domain), anticorps NOL3, anticorps Nol3

Sujet: Nop30 Antibody: Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and the caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. An alternate splicing isoform of ARC was identified as Nop30. While ARC interacts with caspase-2 and -8 and suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3, Nop30 multimerizes and binds to the splicing factor SRp30c and may act to influence alternative splice site selection in vivo. The Nop30 antibody will not detect ARC protein.

ID gène: 8996

NCBI Accession: NP_001171986

UniProt: O60936