FAIM anticorps (C-Term)

N° du produit ABIN6990345

Cet anticorps anti-FAIM est un anticorps Lapin Polyclonal détectant FAIM dans WB et ELISA. Adapté pour Humain et Souris.

Aperçu rapide pour FAIM anticorps (C-Term) (ABIN6990345)

Antigène: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FAIM anticorps

Épitope: C-Term

Purification: FAIM Antibody is affinity chromatography purified via peptide column.

Immunogène: FAIM antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human FAIM. The immunogen is located within the last 50 amino acids of FAIM.

Isotype: IgG

Information d'application

Indications d'application: FAIM antibody can be used for detection of FAIM by Western blot at 5 - 10 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: FAIM Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: FAIM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FAIM

Antigène: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Autre désignation: FAIM

Sujet: FAIM Antibody: The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite outgrowth in different neuronal systems by a mechanism involving the activation of NF-κ,B and the Ras-ERK pathway.

ID gène: 55179

NCBI Accession: NP_060617

UniProt: Q9NVQ4