CIDEB anticorps (AA 100-150)

N° du produit ABIN6990347

L’anticorps Lapin Polyclonal anti-CIDEB a été validé pour ELISA, WB, IF et IHC (p). Il convient pour détecter CIDEB dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CIDEB anticorps (AA 100-150) (ABIN6990347)

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEB est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CIDEB anticorps

Épitope: AA 100-150

Specificité: CIDE-B antibody has no cross activity to CIDE-A.

Purification: CIDE-B Antibody is affinity chromatography purified via peptide column.

Immunogène: CIDE-B antibody was raised against a peptide corresponding to 14 amino acids near the center of human CIDE-B. The immunogen is located within amino acids 100 - 150 of CIDE-B.

Isotype: IgG

Information d'application

Indications d'application: CIDE-B antibody can be used for detection of CIDE-B by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CIDE-B Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CIDE-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CIDEB

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Autre désignation: CIDE-B

Sujet: CIDE-B Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow.

ID gène: 27141

UniProt: Q9UHD4