NKIRAS2 anticorps (C-Term)

N° du produit ABIN6990382

Cet anticorps Lapin Polyclonal détecte spécifiquement NKIRAS2 dans ELISA et WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour NKIRAS2 anticorps (C-Term) (ABIN6990382)

Antigène: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKIRAS2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-NKIRAS2 anticorps

Épitope: C-Term

Purification: KappaB ras2 Antibody is affinity chromatography purified via peptide column.

Immunogène: KappaB ras2 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human KappaB ras2. The immunogen is located within the last 50 amino acids of KappaB ras2.

Isotype: IgG

Information d'application

Indications d'application: KappaB ras2 antibody can be used for detection of KappaB ras1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KappaB ras2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KappaB ras2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NKIRAS2

Antigène: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Autre désignation: KappaB ras2

Sujet: KappaB ras2 Antibody: KappaB ras-1 (κ,B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Iκ,B (Iκ,B), an inhibitor of the transcription factor NF-κ,B. Iκ,B exists in two homologous forms, Iκ,B-alpha and Iκ,B-beta, although Iκ,B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Iκ,B-alpha-NF-κ,B complexes can shuttle in and out of the nucleus, Iκ,B-beta-NF-κ,B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Iκ,B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Iκ,B-beta and regulating the rate of degradation of Iκ,B-beta. This antibody is specific for kappaB-ras2 and has no cross-reactivity to kappaB-ras1.

ID gène: 28511

NCBI Accession: NP_060065

UniProt: Q9NYR9