TRAF3IP2 anticorps (N-Term)

N° du produit ABIN6990385

Cet anticorps Lapin Polyclonal détecte spécifiquement TRAF3IP2 dans WB, ELISA, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TRAF3IP2 anticorps (N-Term) (ABIN6990385)

Antigène: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3IP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TRAF3IP2 anticorps

Épitope: N-Term

Purification: CIKS Antibody is affinity chromatography purified via peptide column.

Immunogène: CIKS antibody was raised against a 14 amino acid peptide near the amino terminus of human CIKS. The immunogen is located within the first 50 amino acids of CIKS.

Isotype: IgG

Information d'application

Indications d'application: CIKS antibody can be used for detection of CIKS by Western blot at 1 μ,g/mL. A band at approximately 63 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CIKS Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CIKS antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TRAF3IP2

Antigène: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Autre désignation: CIKS

Sujet: CIKS Antibody: Nuclear factor kappa B (NF-κ,B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κ,B associates with Iκ,B proteins in the cell cytoplasm, which inhibit NF-κ,B activity. Iκ,B is phosphorylated by Iκ,B kinase (IKK) complex that contains IKKα, IKKβ, and IKKγ,. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-κ,B activator 1). CIKS directly interacts with IKKγ,. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.

Poids moléculaire: 63 kDa

ID gène: 10758

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response