PAK7 anticorps (AA 240-290)

N° du produit ABIN6990413

Détail du produit anti-PAK7 anticorps

Antigène: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Épitope: AA 240-290

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: PAK5 Antibody is affinity chromatography purified via peptide column.

Immunogène: PAK5 antibody was raised against a 13 amino acid synthetic peptide from near the center of human PAK5. The immunogen is located within amino acids 240 - 290 of PAK5.

Isotype: IgG

Information d'application

Indications d'application: PAK5 antibody can be used for the detection of PAK5 by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PAK5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PAK5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PAK7

Antigène: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Autre désignation: PAK5 (PAK7 Produits)

Synonymes: anticorps PAK5, anticorps pak5, anticorps 2900083L08Rik, anticorps 6430627N20, anticorps Pak5, anticorps PAK-5, anticorps PAK-7, anticorps p21 (RAC1) activated kinase 5, anticorps p21 (RAC1) activated kinase 5 L homeolog, anticorps p21 protein (Cdc42/Rac)-activated kinase 7, anticorps p21 (RAC1) activated kinase 7, anticorps PAK5, anticorps pak5.L, anticorps Pak7

Sujet: PAK5 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both. Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth. Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.

ID gène: 57144

UniProt: Q9P286