BCL2L10 anticorps (N-Term)

N° du produit ABIN6990431

Détail du produit anti-BCL2L10 anticorps

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Épitope: AA 90-140, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: Bcl-B Antibody is affinity chromatography purified via peptide column.

Immunogène: Bcl-B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human Bcl-B. The immunogen is located within amino acids 90 - 140 of Bcl-B.

Isotype: IgG

Information d'application

Indications d'application: Bcl-B antibody can be used for the detection of Bcl-B by Western blot at 1 - 2 μ,g/mL. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Bcl-B Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Bcl-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BCL2L10

Antigène: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Autre désignation: Bcl-B (BCL2L10 Produits)

Synonymes: anticorps BCL-B, anticorps Boo, anticorps Diva, anticorps AA420380, anticorps AU023065, anticorps C85687, anticorps NR-13, anticorps mcl1l, anticorps nr13, anticorps sb:cb78, anticorps BCL2 like 10, anticorps Bcl2-like 10, anticorps BCL2-like 10 (apoptosis facilitator), anticorps BCL2L10, anticorps Bcl2l10, anticorps bcl2l10

Sujet: Bcl-B Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.

Poids moléculaire: Predicted: 22 kDa

Observed: 26 kDa

ID gène: 10017

NCBI Accession: NP_065129

UniProt: Q9HD36

Pathways: Positive Regulation of Endopeptidase Activity