BCL2L10 anticorps (N-Term)
Aperçu rapide pour BCL2L10 anticorps (N-Term) (ABIN6990431)
Antigène
Voir toutes BCL2L10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 90-140, N-Term
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Purification
- Bcl-B Antibody is affinity chromatography purified via peptide column.
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Immunogène
- Bcl-B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human Bcl-B. The immunogen is located within amino acids 90 - 140 of Bcl-B.
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Isotype
- IgG
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Indications d'application
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Bcl-B antibody can be used for the detection of Bcl-B by Western blot at 1 - 2 μ,g/mL. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Bcl-B Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- Bcl-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
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Autre désignation
- Bcl-B
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Sujet
- Bcl-B Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.
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Poids moléculaire
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Predicted: 22 kDa
Observed: 26 kDa -
ID gène
- 10017
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NCBI Accession
- NP_065129
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UniProt
- Q9HD36
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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