BCL2L14 anticorps (N-Term)

N° du produit ABIN6990432

Cet anticorps anti-BCL2L14 Polyclonal Lapin (ABIN6990432) détecte spécifiquement BCL2L14 dans WB, ELISA, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCL2L14 anticorps (N-Term) (ABIN6990432)

Antigène: BCL2L14 (BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BCL2L14 anticorps

Épitope: N-Term

Specificité: Although antibody should react with both isoforms, only the Bcl-GS protein has been observed

Purification: Bcl-G Antibody is Ion exchange chromatography purified.

Immunogène: Bcl-G antibody was raised against a peptide corresponding to 15 amino acids near the N-terminus of human Bcl-G. The immunogen is located within the first 50 amino acids of Bcl-G.

Isotype: IgG

Information d'application

Indications d'application: Bcl-G antibody can be used for detection of Bcl-G by Western blot at 2.5 to 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Bcl-G Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Bcl-G antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BCL2L14

Antigène: BCL2L14 (BCL2-Like 14 (Apoptosis Facilitator) (BCL2L14))

Autre désignation: Bcl-G

Sujet: Bcl-G Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.

ID gène: 79370

NCBI Accession: NM_030766

UniProt: Q9BZR8