Anthrax Toxin Lethal Factor anticorps (C-Term)

N° du produit ABIN6990499

Cet anticorps Lapin Polyclonal détecte spécifiquement Anthrax Toxin Lethal Factor dans ELISA. Il présente une réactivité envers Bacillus anthracis.

Aperçu rapide pour Anthrax Toxin Lethal Factor anticorps (C-Term) (ABIN6990499)

Antigène: Anthrax Toxin Lethal Factor (Lef)

Reactivité: Bacillus anthracis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Anthrax Toxin Lethal Factor est non-conjugé

Application: ELISA

Détail du produit anti-Anthrax Toxin Lethal Factor anticorps

Épitope: C-Term

Purification: Anthrax Lethal Factor Antibody is affinity chromatography purified via peptide column.

Immunogène: Anthrax lethal factor antibody antibody was raised against a synthetic peptide corresponding to 16 amino acids near the carboxy terminus of the Anthrax lethal factor protein. The immunogen is located within the last 50 amino acids of Anthrax Lethal Factor.

Isotype: IgG

Information d'application

Indications d'application: Anthrax lethal factor antibody can be used for the detection of Anthrax LF protein in ELISA. It will detect 10 ng of free peptide at 1 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Anthrax Lethal Factor Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Anthrax Lethal Factor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Anthrax Toxin Lethal Factor

Antigène: Anthrax Toxin Lethal Factor (Lef)

Autre désignation: Anthrax Lethal Factor

Sujet: Anthrax Lethal Factor Antibody: Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface, these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF, the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. LF is the primary toxin of anthrax and functions as a highly specific protease that cleaves members of the mitogen-activated protein kinase kinase (MAPKK) family near their amino terminus, interfering with MAPK signaling and inducing apoptosis.

ID gène: 3361711

UniProt: P15917