RPS6K1 (AA 600-650), (C-Term) anticorps

N° du produit ABIN6990539

L’anticorps anti-RPS6K1 Polyclonal Lapin est utilisé pour la détection de RPS6K1 dans des échantillons de Humain. Il a été validé pour ICC, ELISA, WB et IF.

Aperçu rapide pour RPS6K1 (AA 600-650), (C-Term) anticorps (ABIN6990539)

Antigène: RPS6K1

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunocytochemistry (ICC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit

Épitope: AA 600-650, C-Term

Purification: RPS6K1 Antibody is affinity chromatography purified via peptide column.

Immunogène: RPS6K1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human RPS6K1. The immunogen is located within amino acids 600 - 650 of RPS6K1.

Isotype: IgG

Information d'application

Indications d'application: RPS6K1antibody can be used for the detection of RPS6K1 by Western blot at 2.5 - 10 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: RPS6K1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: RPS6K1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détail du antigène

Antigène: RPS6K1

Sujet: RPS6K1 Antibody: Ribosomal protein S6 kinase 1 (RPS6K1) is the best characterized effector of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. Nutrients and growth factors stimulate a complex including TOR, raptor (regulatory associated protein of TOR), and GbetaL to phosphorylate RPS6K1 and the eukaryotic initiation factor 4E binding protein (4EBP1), leading to increased protein synthesis and cell growth. RPS6K1 is thought to desensitize tissues to insulin as mice deficient in RPS6K1 have been shown to be hypersensitive to insulin and impervious to obesity-induced insulin resistance seen in wild type obese mice.

ID gène: 6195

UniProt: Q15418