ADIPOQ anticorps (N-Term)

N° du produit ABIN6990546

Cet anticorps anti-ADIPOQ est un anticorps Lapin Polyclonal détectant ADIPOQ dans WB, ELISA et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ADIPOQ anticorps (N-Term) (ABIN6990546)

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADIPOQ est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ADIPOQ anticorps

Épitope: AA 40-90, N-Term

Purification: Adiponectin Antibody is affinity chromatography purified via peptide column.

Immunogène: Adiponectin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human adiponectin. The immunogen is located within amino acids 40 - 90 of Adiponectin.

Isotype: IgG

Information d'application

Indications d'application: Adiponectin antibody can be used for the detection of adiponectin by Western blot at 1 to 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 1 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Adiponectin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Adiponectin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ADIPOQ

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Autre désignation: Adiponectin

Sujet: Adiponectin Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike the CTRPs, which are expressed in a wide variety of tissues, adiponectin is reported to be expressed exclusively by differentiated adipocytes. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It is present in high levels in normal human plasma, but is reduced in obese subjects and often in those with increased insulin resistance and type 2 diabetes, suggesting that adiponectin may be a useful pharmacological target in various metabolic diseases.

ID gène: 9370

NCBI Accession: NP_004788

UniProt: Q15848