IL23 anticorps (C-Term)

N° du produit ABIN6990631

Détail du produit anti-IL23 anticorps

Antigène: IL23 (Interleukin 23 (IL23))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL23 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Purification: IL-23 Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-IL-23 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of mature human IL-23. The immunogen is located the last 50 amino acids of IL-23.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-4 μ,g/mL, ICC: 10 μ,g/mL, IF: 20 μ,g/mL, IHC: 5 μ,g/mL.

Antibody validated: Western Blot, Immunocytochemistry, Immunofluorescence and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-23 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IL-23 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IL23

Antigène: IL23 (Interleukin 23 (IL23))

Autre désignation: IL-23 (IL23 Produits)

Synonymes: anticorps IL-23, anticorps p19, anticorps SGRF, anticorps il23p19, anticorps interleukin 23, alpha subunit p19, anticorps interleukin 23 subunit alpha, anticorps Il23a, anticorps IL23A

Sujet: IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-α, from activated T cells, and can stimulate macrophages to produce TNF-α, and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.

Poids moléculaire: Predicted: 21kD

Observed: 22 kD kDa

ID gène: 51561

UniProt: Q9NPF7