LY86 anticorps (C-Term)

N° du produit ABIN6990647

Détail du produit anti-LY86 anticorps

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LY86 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: MD-1 Antibody is affinity chromatography purified via peptide column.

Immunogène: MD-1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human MD-1. The immunogen is located within the last 50 amino acids of MD-1.

Isotype: IgG

Information d'application

Indications d'application: MD-1 antibody can be used for the detection of MD-1 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MD-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MD-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LY86

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Autre désignation: MD-1 (LY86 Produits)

Synonymes: anticorps MD-1, anticorps MMD-1, anticorps dJ80N2.1, anticorps MD1, anticorps LY86, anticorps lymphocyte antigen 86, anticorps LY86, anticorps Ly86

Sujet: MD-1 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

ID gène: 9450

NCBI Accession: NP_004262

UniProt: O95711

Pathways: Toll-Like Receptors Cascades