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Cyclin O anticorps (N-Term)

CCNO Reactivité: Humain, Souris, Rat ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6990651
  • Antigène Voir toutes Cyclin O (CCNO) Anticorps
    Cyclin O (CCNO)
    Épitope
    • 13
    • 8
    • 5
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 23
    • 4
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 23
    • 1
    Lapin
    Clonalité
    • 24
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp Cyclin O est non-conjugé
    Application
    • 19
    • 17
    • 3
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Specificité
    At least two isoforms of Cyclin O are known to exist, this antibody will recognize both isoforms.
    Purification
    Cyclin O Antibody is affinity chromatography purified via peptide column.
    Immunogène
    Cyclin O antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Cyclin O. The immunogen is located within the first 50 amino acids of Cyclin O.
    Isotype
    IgG
    Top Product
    Discover our top product CCNO Anticorps primaire
  • Indications d'application
    Cyclin O antibody can be used for the detection of Cyclin O by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Cyclin O Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    Cyclin O antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    Cyclin O (CCNO)
    Autre désignation
    Cyclin O (CCNO Produits)
    Synonymes
    anticorps RGD1565217, anticorps ccnu, anticorps udg2, anticorps ung2, anticorps CCNU, anticorps MGC131111, anticorps C86987, anticorps Ccnu, anticorps E130318K11, anticorps Ung2, anticorps UDG2, anticorps cyclin O, anticorps cyclin O L homeolog, anticorps Ccno, anticorps ccno, anticorps CCNO, anticorps ccno.L
    Sujet
    Cyclin O Antibody: Cyclin O, also known as CCNO, has recently been identified as a Cdk1- and Cdk2-activating cyclin specific to apoptosis in lymphoid cells. Cyclin O binds to and activates Cdk2 in response to instrinsic apoptotic stimuli such as glucocorticoids or DNA-damaging agents. Supression of Cyclin O expression by shRNA leads to the inhibition of glucocorticoid and DNA-damage-induced apoptosis due to a failure of apical caspase activation while leaving the CD95 death receptor-mediated apoptosis intact. Note: this gene, which had a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase. A later publication identified this gene's product as a cyclin protein family member.
    Poids moléculaire
    39 kDa
    ID gène
    10309
    NCBI Accession
    NP_066970
    UniProt
    P22674
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