SAMHD1 anticorps (C-Term, pThr592)

N° du produit ABIN6990713

L’anticorps Lapin Polyclonal anti-SAMHD1 a été validé pour WB, ELISA, IF et IHC. Il convient pour détecter SAMHD1 dans des échantillons de Humain et Souris.

Aperçu rapide pour SAMHD1 anticorps (C-Term, pThr592) (ABIN6990713)

Antigène: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAMHD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-SAMHD1 anticorps

Épitope: C-Term, pThr592

Specificité: Phospho-SAMHD1 antibody will only detect the phosphorylated form of SAMHD1.

Purification: SAMHD1 (phospho Thr592) antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-SAMHD1 (phospho Thr592) antibody was raised against a phosphorylated peptide corresponding to 18 amino acids near the carboxy terminus of human Phospho-SAMHD1 surrounding T592.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.05-1 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SAMHD1 (phospho Thr592) antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SAMHD1 (phospho Thr592) antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SAMHD1

Antigène: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Autre désignation: SAMHD1

Sujet: The SAM domain and HD domain 1 (SAMHD1) protein is upregulated in response to viral infection and is thought to play a role in innate immunity (1). SAMHD1 blocks the infection of HIV-1 and SIVdeltaVpx before reverse transcription in macrophages and dendritic cells (2), and this restriction is regulated by phosphorylation of SAMHD1 (3). Mutations in this gene have been associated with Aicardi-Goutieres syndrome (1).

Poids moléculaire: Predicted: 72kD

Observed: 72 kD kDa

ID gène: 25939

NCBI Accession: NP_056289

UniProt: Q9Y3Z3