NRN1 anticorps (AA 70-120)
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- Antigène Voir toutes NRN1 Anticorps
- NRN1 (Neuritin 1 (NRN1))
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Épitope
- AA 70-120
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NRN1 est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- Neuritin Antibody is affinity chromatography purified via peptide column.
- Immunogène
- Neuritin antibody was raised against a 20 amino acid synthetic peptide from near the center of human neuritin. The immunogen is located within amino acids 70 - 120 of Neuritin.
- Isotype
- IgG
- Top Product
- Discover our top product NRN1 Anticorps primaire
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- Indications d'application
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Neuritin antibody can be used for detection of Neuritin by Western blot at 5 and 10 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Neuritin Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- Neuritin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- NRN1 (Neuritin 1 (NRN1))
- Autre désignation
- Neuritin (NRN1 Produits)
- Synonymes
- anticorps NRN, anticorps dJ380B8.2, anticorps 0710008J23Rik, anticorps Cpg15, anticorps Nrn, anticorps neuritin, anticorps nrn1, anticorps zgc:92828, anticorps NRN1, anticorps cpg15, anticorps nrn, anticorps nrn1-a, anticorps nrn1-b, anticorps nrn1b, anticorps neuritin 1, anticorps neuritin 1a, anticorps neuritin 1 S homeolog, anticorps neuritin 1 L homeolog, anticorps NRN1, anticorps Nrn1, anticorps nrn1a, anticorps nrn1, anticorps nrn1.S, anticorps nrn1.L
- Sujet
- Neuritin Antibody: As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.
- Poids moléculaire
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Predicted: 16 kDa
Observed: 15 kDa - ID gène
- 51299
- NCBI Accession
- NP_057672
- UniProt
- Q9NPD7
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