CRLF2 anticorps (AA 140-190)

N° du produit ABIN6990749

L’anticorps anti-CRLF2 Polyclonal Lapin est utilisé pour la détection de CRLF2 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC (p) et IF.

Aperçu rapide pour CRLF2 anticorps (AA 140-190) (ABIN6990749)

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRLF2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-CRLF2 anticorps

Épitope: AA 140-190

Specificité: At least two isoforms of TSLP-R are known to exist, this antibody will recognize both isoforms.

Purification: TSLP Receptor Antibody is affinity chromatography purified via peptide column.

Immunogène: TSLP Receptor antibody was raised against a 19 amino acid synthetic peptide from near the center of human TSLP receptor. The immunogen is located within amino acids 140 - 190 of TSLP Receptor.

Isotype: IgG

Information d'application

Indications d'application: TSLP-R antibody can be used for detection of TSLP-R by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TSLP Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TSLP Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CRLF2

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Autre désignation: TSLP Receptor

Sujet: TSLP Receptor Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells, co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.

Poids moléculaire: Predicted: 28, 41 kDa

Observed: 53 kDa

ID gène: 57914

NCBI Accession: NP_071431

UniProt: Q8CII9